Publications

Kaur G, Singh NK. Inflammation and retinal degenerative diseases. Neural Regen Res. 18: 513-518, 2023.

Kaur G, Verma SK, Singh D, Singh NK. Role of G-Proteins and GPCRs in Cardiovascular Pathologies. Bioengineering (Basel). 10: 76, 2023. 

Sharma D, Singh NK. The Biochemistry and Physiology of A Disintegrin and Metalloproteinases (ADAMs and ADAM-TSs) in Human Pathologies. Rev Physiol Biochem Pharmacol. 184: 69-120, 2023.

Sharma D, Kaur G, Bisen S, Sharma A, Ibrahim AS, Singh NK. IL-33 via PKCμ/PRKD1 Mediated α-Catenin Phosphorylation Regulates Endothelial Cell-Barrier Integrity and Ischemia-Induced Vascular Leakage. Cells 12: 703, 2023.

Gogoi P, Kaur G, Singh NK. Nanotechnology for colorectal cancer detection and treatment. World J Gastroenterol. 28: 6497-6511, 2022.

Sharma D, Bisen S, Kaur G, Van Buren EC, Rao GN, Singh NK. IL-33 enhances Jagged1 mediated NOTCH1 intracellular domain (NICD) deubiquitination and pathological angiogenesis in proliferative retinopathy. Commun Biol. 5: 479, 2022.

Kaur G, Singh NK. The Role of Inflammation in Retinal Neurodegeneration and Degenerative Diseases. Int. J. Mol. Sci. 23: 386, 2022.

Sharma R, Sharma D, Hazlett LD, Singh NK. Nano-Biomaterials for Retinal Regeneration. Nanomaterials (Basel) 11: 1880, 2021. PMCID: PMC8399153.

Boro M, Govatati S, Kumar R, Singh NK, Pichavaram P, Traylor JG Jr, Orr AW, Rao GN. Thrombin-Par1 signaling axis disrupts COP9 signalosome subunit 3-mediated ABCA1 stabilization in inducing foam cell formation and atherogenesis. Cell Death Differ. 28: 780-798, 2021.  PMCID: PMC7862243.

Kumar R, Mani AM, Singh NK, Rao GN. PKCθ-JunB axis via upregulation of VEGFR3 expression mediates hypoxia-induced pathological retinal neovascularization. Cell Death Dis. 11: 325, 2020. PMCID: PMC7206019.

Raghavan S*, Singh NK*, Gali S, Mani AM, Rao GN. Response by Raghavan et al to Letter Regarding Article, "Protein Kinase Cθ via Activating Transcription Factor 2-Mediated CD36 Expression and Foam Cell Formation of Ly6C(hi) Cells Contributes to Atherosclerosis". Circulation 139: 2079-2080, 2019. *(co-first author)

Singh NK, Rao GN. Emerging role of 12/15-Lipoxygenase (ALOX15) in human pathologies. Prog Lipid Res. 73: 28-45, 2019. PMCID: PMC6338518.

Raghavan S*, Singh NK*, Gali S, Mani AM, Rao GN. Protein Kinase Cθ Via Activating Transcription Factor 2-Mediated CD36 Expression and Foam Cell Formation of Ly6C(hi) Cells Contributes to Atherosclerosis. Circulation 138: 2395-2412, 2018. *(co-first author)

Singh NK, Janjanam J, Rao GN. p115 RhoGEF activates the Rac1 GTPase signaling cascade in MCP1 chemokine-induced vascular smooth muscle cell migration and proliferation. J Biol Chem. 292: 14080-14091, 2017. PMCID: PMC5572933.

Singh NK, Kotla S, Kumar R, Rao GN. Cyclic AMP Response Element Binding Protein Mediates Pathological Retinal Neovascularization via Modulating DLL4-NOTCH1 Signaling. EBioMedicine 2: 1767-1784, 2015. PMCID: PMC4740322.

Singh NK, Kotla S, Dyukova E, Traylor JG Jr, Orr AW, Chernoff J, Marion TN, Rao GN. Disruption of p21-activated kinase 1 gene diminishes atherosclerosis in apolipoprotein E-deficient mice. Nat Commun. 6: 7450, 2015. PMCID: PMC4480433.

Singh NK, Hansen DE 3rd, Kundumani-Sridharan V, Rao GN. Both Kdr and Flt1 play a vital role in hypoxia-induced Src-PLD1-PKCg-cPLA2 activation and retinal neovascularization. Blood 121: 1911-1923, 2013. PMCID: PMC3591809.

Singh NK, Kundumani-Sridharan V, Kumar S, Verma SK, Kotla S, Mukai H, Heckle MR, Rao GN. Protein kinase N1 is a novel substrate of NFATc1-mediated cyclin D1-CDK6 activity and modulates vascular smooth muscle cell division and migration leading to inward blood vessel wall remodeling. J Biol Chem. 287: 36291-36304, 2012. PMCID: PMC3476296.

Singh NK, Kundumani-Sridharan V, Rao GN. 12/15-Lipoxygenase gene knockout severely impairs ischemia-induced angiogenesis due to lack of Rac1 farnesylation. Blood 118: 5701-5712, 2011. PMCID: PMC3217368.

Singh NK, Wang D, Kundumani-Sridharan V, Van Quyen D, Niu J, Rao GN. 15-Lipoxygenase-1-enhanced Src-Janus kinase 2-signal transducer and activator of transcription 3 stimulation and monocyte chemoattractant protein-1 expression require redox-sensitive activation of epidermal growth factor receptor in vascular wall remodeling. J Biol Chem. 286: 22478-27488, 2011. PMCID: PMC3121393.